PIMP3 is a Javascript MP3 player that uses Scriptaculous and Prototype. All you have to do is provide an MP3 track list in JSON format (using AJAX and a server side script).

The look and feel of the PIMP3 is entirely skinnable by editing the CSS file. Features include configurable runtime options such as autostart and random playback order of tracks.

Will be interesting to see if this can be converted to use jQuery.

For more information: PIMP3